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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

史蒂夫?乔布斯(Steve Jobs)去世后的三年中,维权投资者对苹果发起了攻击,一些人对没有乔布斯的苹果是否还能成功也失去了信心,但现年54岁的库克一直沉着应对。今年,他走出了前任的影子,以自己的一套价值观和议程给苹果公司打上了印记:他引进了新鲜人才,改变了苹果管理巨额现金的方式,扩大了苹果与外部的合作,更加关注社会问题。
Employment growth exceeded projections.

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

奥运会是世界各国放下分歧、从事体育运动的时刻。不过这究竟能否付诸实践,还是有争议的。虽然运动员们一定会专注于比赛,不过长期存在的分歧很难会被他们的祖国遗忘,即使是暂时遗忘。
“The Man Who Knew is an impressive work of scholarship,” Lionel Barber, editor of the FT and chair of the book award judges, said. “It’s a masterpiece of political economy and, above all, it’s a great and enjoyable read.”

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
From the themed collection: 中介欠房租 承租人被判搬离
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

Summly和雅虎拒绝对交易的条款置评。

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

今年年底标普500(S&P 500)指数会在2650点上方吗?

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

去年,中国工商银行的每股盈利为0.77元人民币,低于上一年的0.78元人民币,税前每股分红为0.2333元人民币,低于上一年的0.2554元人民币。
Jose's mother Inma Quesada told the El Pais daily that her son "wanted to buy instruments" for his band Los Salerosos (loosely translated as "The Salties"), in which he plays the trumpet.
Spielman was sifting through dirt at the Emek Tzurim national park on the slopes of the Mount of Olives in Jerusalem when she noticed the small rectangular object.
这是悬在全球经济头顶的最大问题,也是最大风险。

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
From the themed collection: 京津冀建材向绿色功能转变提速
Perspective

Trends and targets in antiviral phototherapy

In the past two decades, several campus poisoning incidents have sparked mass debates and concerns about students' psychological development and support.
Rogers, unhappy with the turn of events, decided to leave the show after the first three seasons. The breach of contract led to a multi-million dollar lawsuit. Ironically, Wayne Rogers had never signed his contract to begin with (he had a problem with a morals clause). The lawsuit was thrown out. You could say Rogers got the last laugh, but since M·A·S·H went on for eight more seasons and Rogers' never reached the same career success again, the last laugh might be a relative concept.
● “教皇方济各公开宣称支持特朗普”
n. 轨道(track的复数);磁道;轮胎

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

人类在过去50年的平均寿命比人类存在的20万年中的平均寿命要长的多。目前,人类的平均寿命是70岁,1950年的平均寿命是47岁,两者存在很大的差异。

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

《老友记》中没有露骨的内容、不干净的台词或是黄段子,但它的幽默感却丝毫不减,为这个电视剧总喜欢裹挟着露骨内容的年代带来一阵清新之风。

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
From the themed collection: 2017家居圈大变革 你准备好了吗?
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

智能皮带
Whatever one's view, two further points for and against Russia's global standing are undeniable:

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

8. 斯特吉尔·辛普森(Sturgill Simpson),《乡村音乐的大现代之声》(Matamodern Sound in Country Music),High Top Mountain。一支极为聪敏的乐队做出复古的改革:乡村乐中曾经发生过这样的事。但在斯特吉尔·辛普森突破性的第二张专辑中,他把这一点变成了可适应环境的标志,就建立在他那动人而通透的男中音之上。
税:2014年约为16866美元(约合人民币10.8万元)

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

[?'θ?:riti]
6. “Taxi”(Jafar Panahi)

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

流行天后嘎嘎小姐凭借她在HBO热门短剧《美国恐怖故事:旅馆》中扮演的反面角色获得了最佳女主角的奖杯。当她上台领奖时,她的情绪很激动。
Most of the cellphones sold in 2016 are smart phones installed with the Android system and 4G ready, according to the report.
马丁沃尔夫(Martin Wolf)
The unexpected drop in 2013 came in spite of new policies--such as the city's 72- hour visa waiver for transit passengers--that were introduced in an attempt to nurture China's tourism industry.

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

More importantly, their inventions may even eventually be turned into products that benefit mankind.

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
From the themed collection: 长春警方立案调查长生生物
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

8.Form or Join a Study Group
与此同时,达洛伊西奥开始环游世界,到处参加会议,并结识其他潜在的投资人。他给每一位结识的人都留下极深的印象。温布尔顿国王学院中学(King’s College School)的校长安德鲁?霍尔斯(Andrew Halls)评价道,他成熟得可怕,他在各种状况下仍保持着清晰的思维,这令我这个54岁的人都觉得惊讶。

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

过去一年中,亚利桑那州最大的赢家是建筑和休闲/酒店行业,这两个行业共增加了超过1万个就业机会。其他快速增长的行业包括商业服务、金融活动、教育和医疗服务。

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

One might expect that online programmes would appeal proportionately more to women than full-time programmes due to their flexibility. How-ever, data from the 2016 rankings show that women account for 30 per cent of enrolled students compared with 35 per cent for full-time programmes.

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

此外,有6个地区的GDP增速低于7%,其中东北的辽宁省以负增长垫底。
3.你必须支持我所支持的队伍。
However, others argued that doctors' hands may be forced by an unfair system. "As a patient, I'm more concerned about whether they can cure my illness rather than how many papers they've published," another netizen said.
Inventors Bryan Carpenter and Bland Hoke were inspired by their passion for the outdoors, and decided to come up with a creative way to bring their hammocks everywhere they go.

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

STEP 8: PRACTICE the method of loci or roman room, or at least pretend to
大型企业PMI为53.1,比上月下降0.7个百分点;中型企业PMI为49.8,回落1.3个百分点,意味着进入轻度收缩。小型企业PMI为49,下降0.4个百分点,意味着收缩加剧。
You've usually stated in pastinterviews that you have connections to your characters. In Aldnoah Zero, whichis currently airing, what do you think is your connection to Inaho?
n. 理解力,智力
vt. 创立,开始,制

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

It is the first time I have been toSan Francisco. It is a very beautiful city. On the first day of our visit wewent to the Golden Gate Bridge. Seeing the bay view was really pleasant.Every time I am watching movies inJapan, the city and the bridge always seem to get destroyed. I didn't know thecity was so beautiful in person.The bridge might not be around nexttime I visit so I'm glad I got to see it.
土耳其部长们近来一直在欧洲各地的土耳其社区举行集会,以争取海外土耳其人对埃尔多安发起的宪法改革的支持——土耳其将于下个月就修宪举行公投。

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

The January-to-November period in the United States this year was the warmest first 11 months of any year on record for the contiguous states. And 2012 will likely surpass 1998 as the warmest year on record for the nation, according to the National Oceanic and Atmospheric Administration.

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

2. Staying too long in a job that you want to leave

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

adj. 在 ... 之前,先,前,以前的
直到最近,Weill Cornell Medical College的科学家们至少在老鼠和猴子身上实现了这一点。这种人造视网膜,它的芯片可以将画面转换为电子信号,而它的微型投影机可以将电子信号转化为投影光线。
n. 学会,学院,协会
"This year's prize concerns a central economic problem: how to match different agents as well as possible," the academy said.

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

这些排行榜是基于某个特定学科的研究能力而做出评价,与综合榜单评价方式不同。
Amid all of the current talk about whether government law enforcement agencies should be able to legally force Apple to unlock an iPhone to look for evidence, there is a machine available now at London's Fone Fun Shop that will find the four-digit passcode used to lock down an iPhone. And this device costs only $170.
Chester Bennington
5. 弗莱德·赫什三人组(Fred Hersch Trio),《漂浮》(Floating), Palmetto。赫什目前的钢琴三人组由约翰·艾伯特(John Hébert)担任贝斯,埃里克·麦克菲森(Eric McPherson)担任鼓手,他们有着精确的优雅。这张专辑的结构如同一场夜间俱乐部演出,包括若干重新编配的标准曲,以及几首强劲而充满情感的原创曲,有着强大的表现力。

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

Will the Democrats take back the majority in the midterm election in the US House of Representatives
Please accept my sincere wishes for the New Year. I hope you will continue to enjoy good health.

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

现在似乎可以放心地预言,2017年余下时间会出现更多噪音、甚少进展,而这将继续对贸易和英国经济造成破坏。
The U.S. Veterans Day holiday also coincides with other World War One-era holidays around the world, including Remembrance Day in Britain and the Commonwealth nations of Australia and Canada.
马纳尔·阿尔-谢里夫(Manal al-Sharif)
影片发生在一个夏天,故事里6岁的早熟女孩穆尼整天和一群衣衫褴褛的朋友们捣乱打闹。生活在迪士尼乐园的幻影里,她和反叛却充满爱心的妈妈感情越发深厚。
本田已在美国召回了1000多万辆汽车,修复其安全气囊一项潜在的致命缺陷。这种气囊由日本供应商高田公司制造,其充气装置在发生车祸时会突然爆裂,溅出金属碎片伤及乘客。本田已确认有三起死亡和48起受伤事件与这一问题有关。

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

In February, Maddie joined Sia and Kristen Wiig in a performance of the track for the 2015 Grammy Awards as Kim Kardashian and Kanye West looked on from the front row.
Of the 27 provincial-level regions that outpaced the country's 6.7% GDP growth in 2016, only three regions - Chongqing, Guizhou and Tibet - achieved double-digit growth.
单词extravagant 联想记忆:

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

Since merged airlines often continue to report delay statistics separately, it may take a few years to see how the new American does during holiday travel.
“白”之禁忌

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
From the themed collection: 盘点:我国卫浴行业发展四大亮点
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
From the themed collection: 70城房价连续49个月上涨
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

The alternative analysis is that the shift we have seen over the past three years is the beginning of a long-term structural shift which will see energy prices materially lower in real terms in the next half century than in the last. Those who take this view believe, to put it very simply, that the likely growth in supply is stronger than the growth in demand.
Most of those surveyed for the report mentioned that positive impacts of social media include socializing with acquaintances and taking in more information.
10.American Hustle

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

Kunis was No. 9 on FHM's list last year.
The 30 percent increase is to be driven bymore specialty drug innovation, greater patient access to medicines and reducedimpact from patent expiry dates.
先是“非典”,接下来是全球范围的H5N1以及H1N1流感大爆发。全球化也无能为力。现在地球实际就是一个小村庄,这也使得病毒在几小时内,就能轻而易举地从北京传播到波士顿。2010我们是否会再次遭遇另一场“甲流”?

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

? The failure of a backup generator forced the evacuation of the Langone Medical Center, part of NYU hospital. About 200 patients had to be moved. Officials are investigating why the backup power failed.

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

国家统计局日前在其官网上声称,2017年,衡量通胀的主要指标全国居民消费价格指数(CPI)上涨1.6%,低于3%的全年控制目标。

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

After Google and Apple, are Amazon and Microsoft.
Wang Rongzhen在采访中表示,“我们就是要卖车,如果厂家不提供车型,我们就卖不下去了,也只能退网。”他估计经销商每年亏损300-1000万元。目前,现代汽车在中国有近40家进口经销商,其中30家经销商要求退网赔偿。

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

请接受我们对你及你全家的美好祝福,祝你们新年快乐。
Tuesday’s event at Apple’s new Cupertino headquarters is expected to reveal its much-anticipated 10th-anniversary iPhone, offering significant upgrades to the smartphone’s display, camera and overall design.
intel在…中间+lig选择,收集+ence→从中选出好的→智力;聪明
Google's top 10 searches for 2017–U.S.

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

According to the financial data provider Wind Information Co Ltd, listed companies in China's A-share market earned 2.47 trillion yuan in profits last year. Of those listed companies, 2000 plan to pay out 700 billion yuan to their shareholders.
Bringing harmony to Apple’s internal fiefdoms has not been easy. There is still “huge tension” inside Apple, according to one person who has worked with the company for many years. “That tension is something he uses to run the company but it can be dangerous.”

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

n. 理解力,智力
[iks'tr?v?g?nt]

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

The jobs were ranked based on the following attributes, with much of the data coming from the Bureau of Labor Statistics: “income, outlook, environmental factors, stress and physical demands.”

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
From the themed collection: 智能家居产业将迎爆发期
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

著名美国谐星梅丽莎?麦卡西收入为3300万美元,比去年增加了1000万美元。
现任美国主席奥巴马的内阁共有7名女性,17名男性,克林顿曾是其中一员。
● “一男子持枪自拍时不小心把自己JJ射了”
第二晚(12月9日)的苏富比(Sotheby’s)拍卖会共拍得2260万英镑(含佣金),比佳士得前晚的表现要好得多,不过也只是略高于2180万英镑(不含佣金)的最低估价。44件拍品中有15件流拍,比例达34%。

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

开始布置吧。你是不是已经有所感悟了呢?那么赶紧去布置一个优雅和个性的办公桌吧,心动不如行动哦。
If the oldest man ever elected president can “tweet like a kindergartner,” why not flip the script and see if a youngster can be elected to office and govern wisely?

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

Growth in the key sectors driving China’s economy softened last month, according to official gauges tracking activity at manufacturing, services and construction businesses.
《胡润百富榜》追踪逾2000名净财富在3亿美元或以上的民营企业家,今年的榜单新增了179位富豪。
"The essential question of the Sino-Japanese relationship is if Japan can accept the fact that China is growing stronger and more powerful." CUI TIANKAI, member of the CPPCC National Committee and vice-minister of foreign affairs

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

A BuzzFeed News analysis has identified the 50 fake news stories that attracted the most engagement on Facebook this year. Together they totaled 21.5 million likes, comments, and shares. Of these stories, 23 were about US politics, two were about women using their vaginas as murder weapons, and one was about a clown doll that actually was a person the whole time.
田径、手球、自行车、场地赛、公路赛、山地赛、小轮车(BMX)、马术、足球、沙滩排球、
我在世界最知名的公司之一找到了一份工作,对此学校的关系网络起到了重要的作用,鹿特丹管理学院(Rotterdam School of Management)一名毕业生表示,这家公司是学校的一个公司合作伙伴,因此我基本上是在我的邮箱收到工作申请书的。

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

The actor - who is heavily tipped for his first Oscar this year - won the gong for best actor in a film drama for his role in The Revenant, beating rivals including Eddie Redmayne who was nominated for The Danish Girl.
(可可英语版权所有,未经允许请勿转载)

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
From the themed collection: 棚改贷款审批权限未上收总行
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
From the themed collection: 以绿色发展引领乡村振兴
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

Scientists confirmed Monday that a skeleton found under a carpark in the English city of Leicester was that of King Richard III, in a bizarre end to a 500-year-old historical mystery.
人们可能会认为,由于课程的灵活性,与全日制项目相比,在线MBA项目将更吸引女性。然而,2016年英国《金融时报》在线MBA排行榜的数据显示,女性占总学员数量的30%。在全日制项目中,女学员占到了35%。
时间:2010-05-31 编辑:francie

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

This makes China the country with the second most number of universities included in the Global 400 Subjects, according to the QS rankings. This is only after the United States, which has 164 universities included in the Global 400 subjects. The UK comes third at 78 universities.
4.Virtual Assistant: 17.6 percent increase

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
From the themed collection: 住房租赁REITs酝酿启动
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

Across all European schools, the average salary of alumni three years after graduation ranges from $143,000 for executive MBA graduates to $54,000 for MiM graduates. MBA graduates earned on average $123,000. Spanish and German MiM graduates enjoyed the highest salary three years after graduation, both $70,000 on average. French MBA graduates and Swiss EMBA graduates top their salary scale, with average salaries of $137,000 and $166,000 respectively.
STEP 6: FIND A WATSON
“We sell cars+ , if you don’t give us cars, naturally we won’t be able to go on, we’ll close,” Wang said in an interview, estimating import dealers are losing between 3 million and 10 million yuan a year each. The group seeking compensation represents 30 of the roughly 40 remaining imported Hyundai dealers in the country.

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

英国整体排名第三。“强国”排名第四,“文化影响力”排名第五。

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

那么多的人视而不见,不承认事实。真相是泡沫无处不在,随时准备爆掉。证据越来越多,结论只有显而易见的一个:泡沫破灭的风险最高可达98%。2014年这次崩盘几乎是铁定要发生的,躲过这枚子弹的概率只有区区2%。
根据历史记载,理查三世战败后,其裸露的尸体曾被放在一匹驮马上运往莱斯特,后埋在莱斯特一家方济会修道院的墓地,但没有任何标记。莱斯特位于英国中部。

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

马克?高恩洛夫(Mark Gongloff)在《赫芬顿邮报》(Huffington Post)上警告说:“一季度美国经济增长的大幅降级揭示了经济体挥之不去的疲弱,暴露了华盛顿执迷于财政紧缩的愚蠢,并给美联储最新的乐观打了一记响亮的耳光。”而随着政治局势的恶化,增长速度还会进一步放缓。
梦工厂:内部消费券

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

“A worker sent a text to a colleague saying he was quitting and asked her to forward it to management.”
《帕丁顿熊2》

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

? President Obama declared a "major disaster" in New York and New Jersey. Flooding devastated the coast and more than 2.3 million lost power. The National Guard rescued hundreds from flooding in New Jersey. The governor, Chris Christie, a Republican, said the damage was "unthinkable". He praised the "outstanding" co-operation he had received from Obama.
3.解决问题的好手

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

Derrick Rose

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

然而,由于这些先进的新组件供应紧张,可能会让许多客户在9月之后才能等到新款iPhone。这给Essential或三星(Samsung) Note 8等竞争对手带来了机会;Essential是由安卓(Android)操作系统的联合创始人安迪?鲁宾(Andy Rubin)领导的智能手机制造商,该公司正以其售价699美元的时尚新机型瞄准苹果等竞争对手的高端客户。据信谷歌(Google)也在筹备新版Pixel智能手机,这款手机很受早期试用者欢迎。
该学校校友的总体满意度为95%,比伦敦商学院(London Business School)和德国WHU奥拓贝森管理研究院(WHU Beisheim)高出两个百分点。
Rihanna vs. Rosario Dawson Both stars wore this long satin Dolce & Gabanna dress in different colors.   蕾哈娜和罗莎里奥·道森都穿了这件款式一致颜色不同的D&G
Recipient: Britney Spears

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

祝贺佳节。

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
From the themed collection: 减税降费为经济添动力
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

But the 3D version of the mascot image failed to dodge bullets, as critical netizens sneered at this version: "Reminds me of green and red lights." "Lost all the flair of that ink painting" "What are those balls under its ears?" "It is so ugly that I just want to cry."
或许,在纽约尼克斯夺取NBA总冠军的道路上,缺失的关键就是甜瓜(安东尼的昵称)。噢,不,等等,林书豪才是他们欠缺的一环。然而,无论怎样,甜瓜不会妨碍尼克斯的冠军梦。
China will not overreach its regional influence to seek trade arrangements where the country's due role is not in place.

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

数据显示,在欧洲外的最受游客欢迎20大目的地中,游客的消费主要用于购物,而非就餐。尽管其中很多是世界著名的美食之都。
"We're excited to have these talented artists showcase the powerful contribution music makes to filmmaking," the show's producers Michael De Luca and Jennifer Todd announced in a statement on Friday. "It's a privilege to welcome them to the 90th Oscars stage."

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

凯文·杜兰特
Hopefully the experts come up with a better plan than one that fell flat earlier this year. The country's tourism body unveiled a 'Beautiful China' logo in February to market the country overseas, but the campaign was mocked for its contrast with the many photos of China's not-so-beautiful cities shrouded in pollution.

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
From the themed collection: 深圳:拍地需配建20%自持租赁住房
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

adj. 最高的,至上的,极度的

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

注册人数:503人
一个由8位《沃兹汽车》编辑组成的专家组在10月和11月评估了所有汽车车型使用的44款引擎,测试时间为日常上下班和周末在底特律都市区及附近进行的活动。各位专家根据多项特征进行打分,包括动力和扭矩、燃料经济、噪音、抖动和声振粗糙度、技术以及这些发动机相对于竞争对手的表现。
The pandas did some tai-chi in Trafalgar Square before kicking on at a panda party in Convent Garden as part of the first ever Panda Awareness Week.

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

e出,pi,sode与sell的过去试sold发音一样:出门把pi卖了,这绝对是人生的一个插曲。
3. Portugal is entirely powered by renewable energy for four days
Here is my best guess - and that's all it is - for how the U.S. economy and markets will look in 2010:
n. 宣言,声明 vi. 发表宣言

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

世界知识产权组织总干事弗朗西斯.高锐在记者会上表示“中国的表现必须予以强调,他们的排名排到了第25位,与那些多年来一直位居全球创新指数前列的高收入国家比肩而立。”
The full list of this year's honorees follows.

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

中国的各个创新指标显现出“持续稳健的进步”,高锐表示,“没有理由认为这前进的脚步会停下来。”
尽管欧洲工商管理学院与清华大学的合办项目重新跌至亚军位置,但欧洲工商管理学院自己的EMBA项目的排名却上升3个位置,排在第四位,该项目上次获得第4名是在2011年。
Get ready to see ads from the neighborhood pub on Twitter

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
156 items - Showing page 1 of 3

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And, men are 2.8 times more likely to use this obvious phrase than women.
China's box office sales have increased from 1 billion yuan to 40 billion yuan in the past decade as the industry has adopted more market-oriented reform measures.

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